Chirag B Patel Selected Research

diazobenzenesulfonic acid (DASA)

12/2021	A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma.
1/2021	Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [18F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression.
1/2020	Human biodistribution and radiation dosimetry of [18F]DASA-23, a PET probe targeting pyruvate kinase M2.
1/2020	Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [18F]DASA-23.
12/2018	The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography.

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Chirag B Patel Research Topics

Disease

20	Neoplasms (Cancer) 10/2022 - 04/2007
10	Glioblastoma (Glioblastoma Multiforme) 12/2021 - 09/2017
5	Glioma (Gliomas) 12/2021 - 09/2017
3	Intraoperative Complications 06/2011 - 10/2010
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 01/2013
2	Ulcerative Colitis 07/2011 - 01/2010
1	Cytokine Release Syndrome 01/2022
1	Disease Progression 01/2022
1	Sepsis (Septicemia) 01/2022
1	Seizures (Absence Seizure) 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 01/2022
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022
1	Inflammation (Inflammations) 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 12/2018
1	Neoplasm Metastasis (Metastasis) 12/2015
1	Hypoxia (Hypoxemia) 12/2015
1	Squamous Cell Carcinoma of Head and Neck 12/2015
1	Rhinitis 10/2013
1	Sneezing 10/2013
1	Rhinorrhea 10/2013
1	Hyponatremia 01/2013
1	Hypoglycemia (Reactive Hypoglycemia) 01/2013
1	Acidosis 01/2013
1	Rhinosinusitis 11/2012
1	Sigmoid Diseases 01/2012
1	Anastomotic Leak 01/2011
1	Anus Neoplasms (Anal Cancer) 12/2010
1	Polyps 10/2010
1	Prolapse 01/2010
1	Spinal Cord Injuries (Spinal Cord Injury) 07/2009

Drug/Important Bio-Agent (IBA)

5	diazobenzenesulfonic acid (DASA)IBA 12/2021 - 12/2018
4	Pyruvate KinaseIBA 12/2021 - 12/2018
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2015
2	Biological ProductsIBA 10/2022 - 01/2020
2	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2013
2	LigandsIBA 01/2019 - 12/2018
2	Sevoflurane (Ultane)FDA LinkGeneric 12/2015 - 11/2012
2	Remifentanil (Ultiva)FDA Link 12/2015 - 11/2012
2	Propofol (Diprivan)FDA LinkGeneric 12/2015 - 11/2012
1	Antimitotic AgentsIBA 10/2022
1	axicabtagene ciloleucelIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Midazolam (Versed)FDA LinkGeneric 01/2022
1	Methylprednisolone FDA LinkGeneric 01/2022
1	Lorazepam (Ativan)FDA LinkGeneric 01/2022
1	tocilizumab (atlizumab)FDA Link 01/2022
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2022
1	pembrolizumabIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 05/2021
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 05/2021
1	Peptides (Polypeptides)IBA 01/2020
1	coenzyme Q10 (CoQ10)IBA 01/2020
1	Molecular Probes (Molecular Probe)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	LipidsIBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020
1	Superoxides (Superoxide)IBA 01/2020
1	Glutamic Acid (Glutamate)FDA Link 12/2019
1	Tumor Biomarkers (Tumor Markers)IBA 01/2019
1	B7-H1 AntigenIBA 01/2019
1	Immune Checkpoint InhibitorsIBA 01/2019
1	LuciferasesIBA 01/2019
1	AntibodiesIBA 01/2019
1	Nucleic AcidsIBA 01/2019
1	RadiopharmaceuticalsIBA 12/2018
1	fluorodopa F 18IBA 09/2018
1	AcidsIBA 01/2018
1	Indicators and Reagents (Reagents)IBA 01/2018
1	Firefly LuciferasesIBA 09/2017
1	LactonesIBA 09/2017
1	withaferin AIBA 09/2017
1	Anesthetics (Anesthetic Agents)IBA 12/2015
1	protein kinase PIBA 12/2015
1	nasIBA 10/2013
1	Capsaicin (Zostrix)FDA Link 10/2013
1	Irritants (Vesicants)IBA 10/2013
1	conivaptan (Vaprisol)FDA Link 01/2013
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2013
1	ElectrolytesIBA 01/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2009

Therapy/Procedure

9	Therapeutics 01/2022 - 12/2010
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2018
3	Radiotherapy 01/2020 - 04/2007
3	Length of Stay 12/2013 - 10/2010
2	Intravenous Anesthesia 12/2015 - 11/2012
2	Anesthesia 12/2015 - 11/2012
2	Colectomy 01/2012 - 10/2010
2	Restorative Proctocolectomy 07/2011 - 01/2010
1	Palliative Care (Palliative Therapy) 06/2021
1	Immunotherapy 01/2020
1	Ayurvedic Medicine (Siddha Medicine) 09/2017
1	Conversion to Open Surgery 12/2013
1	Operative Surgical Procedures 07/2011
1	Patient Readmission 01/2011
1	Operative Time 12/2010
1	Proctectomy 12/2010
1	Colonic Pouches (S Pouch) 01/2010